Protective Killed Leptospira borgpetersenii Vaccine Induces Potent Th1 Immunity Comprising Responses by CD4 and T Lymphocytes
نویسندگان
چکیده
BRIAN M. NAIMAN, DAVID ALT, CAROLE A. BOLIN, RICHARD ZUERNER, AND CYNTHIA L. BALDWIN* Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, Massachusetts 01003; Bacterial Diseases of Livestock Research Unit, National Animal Disease Center, USDA Agricultural Research Service, Ames, Iowa 50010; and Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan 48824
منابع مشابه
شناسایی اپی توپهای سلولهای CD4+ T در پروتئین ترشحی MPB51 مایکوباکتریوم توبرکلوزیس در موشهای C57BL/6
Introduction & Objective: Both CD4+ type 1 helper (Th1) cells and CD8+ T cells play effective roles in protection against Mycobacterium tuberculosis infection. DNA vaccine encoding MPB51 can induce Th1-type immune responses and protective immunity upon challenge with M.tuberculosis. This study address to identify T-cell immunodominant epitopes on MPB51 in C57BL/6 mice. Materials & Methods : ...
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تاریخ انتشار 2001